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Healthcare· 7 min read

DEA Registration for New Prescribers

MATE Act training is now required at registration and renewal. Here's the full new-prescriber DEA pathway.

DEA Form 224 registers a practitioner to prescribe controlled substances. State licensure must be active first — DEA will not issue against a pending state license.

Step-by-step

  1. 1

    Confirm state controlled-substance authority

    Many states require a separate state CDS registration before federal DEA.

  2. 2

    Complete MATE Act training

    8 hours of qualifying training on substance-use disorders is required at first registration and each renewal.

  3. 3

    File DEA Form 224 online

    Fee is $888 for a 3-year registration. Select schedules II through V as needed.

  4. 4

    Maintain a tie-breaker address

    Registration ties to a specific practice address. A second location requires a second registration.

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